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IGFALS Antibody (Center)

IGFALS Antibody (Center)

ArtNr	ABC-AP7478c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	IGFALS, ALS, Insulin-like growth factor-binding protein complex acid labile subunit
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Primary Accession	P35858
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this protein are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty.
Bio References	Leong S.R., Baxter R.C.Mol. Endocrinol. 6:870-876(1992) Suwanichkul A.Endocrinology 141:833-838(2000) Liu T., Qian W.-J.J. Proteome Res. 4:2070-2080(2005)
Clonality	Polyclonal
Clone/Animal Names	RB18270
Gene ID	3483
Gene Name	IGFALS
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Legend image 1	Western blot analysis of IGFALS Antibody (Center) (Cat.#AP7478c) in mouse spleen tissue, Jurkat cell line and mouse liver tissue lysates (35ug/lane). IGFALS (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with IGFALS Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	IGFALS Antibody (Center) (Cat. #AP7478c) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	66035
Antigen Region	308-335
Antigen Source	HUMAN
Target/Specificity	This IGFALS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the Central region of human IGFALS.
NCBI Accession	NP_001139478.1; NP_004961.1

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