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CDC2 (CDK1) Antibody (C-term)

CDC2 (CDK1) Antibody (C-term)

ArtNr	ABC-AP7517b
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CDK1, CDC2, CDKN1, Cyclin-dependent kinase 1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDC28A, P34CDC2
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Primary Accession	P06493
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	CDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
Bio References	Chow, J.P., et al., J. Biol. Chem. 278(42):40815-40828 (2003). Nozoe, T., et al., J. Cancer Res. Clin. Oncol. 129(9):498-502 (2003). Margottin-Goguet, F., et al., Dev. Cell 4(6):813-826 (2003). Yuan, H., et al., J. Virol. 77(3):2063-2070 (2003). Manes, T., et al., J. Cell Biol. 161(4):817-826 (2003).
Clonality	Polyclonal
Clone/Animal Names	RB3126
Gene ID	983
Gene Name	CDK1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of anti-CDK1 Pab (Cat. #AP7517b) in A375 cell lysate. CDK1 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	P39951; P11440; P48734
Predicted	B, M, Rat
Isotype	Rabbit Ig
Calculated MW	34095
Antigen Region	230-260
Antigen Source	HUMAN
Target/Specificity	This CDC2 (CDK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CDC2 (CDK1).
NCBI Accession	NP_001777.1; NP_203698.1

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ABC-AP7517b-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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