Aromatase (CYP19A1) Antibody (C-term)

Primary Antibodies; Cancer; Cell Biology; Metabolism; Neuroscience

CYP19A1 is a member of the cytochrome P45 superfamily of enzymes. The cytochrome P45 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in the gene encoding CYP19A1 can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.

RB14708

Purified Rabbit Polyclonal Antibody (Pab)

57883

453-485

WB: 1:1000
WB: 1:1000
IHC-P: 1:10~50