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NTF3 Antibody (Center)

NTF3 Antibody (Center)

ArtNr	ABC-AP7763c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Neurotrophin-3, NTF3, NT-3, Neurotrophic factor, HDNF, Nerve growth factor 2, NGF-2
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Primary Accession	P20783
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	NTF3 is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
Bio References	Hossain, W.A., J. Neurosci. Res. 86 (11), 2376-2391 (2008) Mercader, J.M., Hum. Mol. Genet. 17 (9), 1234-1244 (2008) Kalcheim, C., Proc. Natl. Acad. Sci. U.S.A. 89 (5), 1661-1665 (1992)
Clonality	Polyclonal
Clone/Animal Names	RB14463
Gene ID	4908
Gene Name	NTF3
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	NTF3 Antibody (Center) (Cat.#AP7763c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NTF3 antibody detected the NTF3 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human brain tissue reacted with NTF3 antibody (Center) (Cat.#AP7763c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	P18280; Q06AV0; P20181; P25433; Q08DT3
Predicted	B, C, M, Pig, Rat
Isotype	Rabbit Ig
Calculated MW	29355
Antigen Region	122-151
Antigen Source	HUMAN
Target/Specificity	This NTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human NTF3.
NCBI Accession	NP_001096124.1; NP_002518.1

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