IRAK Antibody (C-term)

Primary Antibodies; Cardiovascular; Immunology; Signal Transduction; Immunity; Innate immunity; Toll receptor signaling; Toll-Like Receptor; Toll-Like receptor signaling

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 5 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.The tyrosine-like kinase (TLK) group consists of 4 tyrosine and serine-threonine kinases such as MLK (mixed-lineage kinase), LISK (LIMK/TESK), IRAK (interleukin-1 receptor-associated kinase), Raf, RIPK (receptor-interacting protein kinase), and STRK (activin and TGF-beta receptors) families.

RB02337

Purified Rabbit Polyclonal Antibody (Pab)

76537

683-712

WB: 1:1000
WB: 1:1000
IHC-P: 1:10~50
IHC-P: 1:50~100
IHC-P: 1:50~100