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B-RAF Antibody (Center)

ArtNr ABC-AP7810C
Hersteller Abcepta
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, FC, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Loewe, R., et al., J. Invest. Dermatol. 123(4):733-736 (2004).
Yamaguchi, T., et al., J. Biol. Chem. 279(39):40419-40430 (2004).
Frattini, M., et al., Oncogene 23(44):7436-7440 (2004).
Tsavachidou, D., et al., Cancer Res. 64(16):5556-5559 (2004).
Gear, H., et al., Invest. Ophthalmol. Vis. Sci. 45(8):2484-2488 (2004).
NCBI NP_004324.2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Serine/threonine-protein kinase B-raf,Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1,BRAF,BRAF1,RAFB1
Similar products BRAF, p94, BRAF1, RAFB1, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, v-Raf murine sarcoma viral oncogene homolog B1
Lieferbar
Manufacturer - Category
Primary Antibodies; Cancer; Cell Biology; Signal Transduction; T cell activation; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling
Manufacturer - Targets
This B-RAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-453 amino acids from the Central region of human B-RAF.
Bio Background
BRAF, a mebmer of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB11677
Gene Name
BRAF
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
C, M
Calculated Molecular Weight
84437
Antigen Source
HUMAN
Antigen Region
424-453
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution
IF: 1:10~50
WB: 1:1000
IHC-P: 1:10~50
FC: 1:10~50
Antigen Type
Synthetic Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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