BRAF Antibody (T400)

ArtNr	ABC-AP7810E
Hersteller	Abcepta
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunohistochemistry Western Blot Primary Antibodies Astrocytoma
Typ	Antibody Polyclonal
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Hingorani, S.R., et al., Cancer Res. 63(17):5198-5202 (2003). Lee, J.W., et al., Br. J. Cancer 89(10):1958-1960 (2003). Davies, H., et al., Nature 417(6892):949-954 (2002). Naoki, K., et al., Cancer Res. 62(23):7001-7003 (2002). Stephens, R.M., et al., Mol. Cell. Biol. 12(9):3733-3742 (1992).
NCBI	NP_004324.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein kinase B-raf,Proto-oncogene B-Raf,p94,v-Raf murine sarcoma viral oncogene homolog B1,BRAF,BRAF1,RAFB1
Similar products	BRAF, p94, BRAF1, RAFB1, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, v-Raf murine sarcoma viral oncogene homolog B1
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Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Signal Transduction; T cell activation; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling; Interleukin signaling
Manufacturer - Targets	This BRAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-408 amino acids from human BRAF.
Bio Background	BRAF, a member of the RAF subfamily of Ser/Thr protein kinases, is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neurons. This cytoplasmic protein is expressed in brain and testis. Defects in BRAF are involved in a wide range of cancers including lung cancer and non-Hodgkin lymphoma (NHL). This protein contains 1 zinc-dependent phorbol-ester and DAG binding domain.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB13721
Gene Name	BRAF
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	M
Calculated Molecular Weight	84437
Antigen Source	HUMAN
Antigen Region	379-408
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:500-2000 WB: 1:500 IHC-P: 1:100 IHC-P: 1:100
Antigen Type	Synthetic Peptide

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Menge: 400 ul

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