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PIK3R2 Antibody (Y464)

PIK3R2 Antibody (Y464)

ArtNr	ABC-AP8028d
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PIK3R2, Phosphatidylinositol 3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, PtdIns-3-kinase regulatory subunit p85-beta
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Primary Accession	O00459
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The family has been classified into 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. PIK3R2 binds to activated Protein Tyrosine Kinases, which are phosphorylated, through its SH2 domain, and acts as an adaptor, mediating the association of the P110 catalytic unit to the plasma membrane.
Bio References	Khan, N.A., et al., J. Neurovirol. 9(6):584-593 (2003). Deregibus, M.C., et al., J. Biol. Chem. 277(28):25195-25202 (2002). Cook, J.A., et al., J. Immunol. 169(1):254-260 (2002). Park, I.W., et al., Blood 97(2):352-358 (2001). Zauli, G., et al., FASEB J. 15(2):483-491 (2001).
Clonality	Polyclonal
Clone/Animal Names	RB13727
Gene ID	5296
Gene Name	PIK3R2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of PIK3R2 (arrow) using rabbit polyclonal PIK3R2 Antibody (T447) (RB13726). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PIK3R2 gene (Lane 2) (Origene Technologies).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q63788; O08908; P23726
Predicted	B, M, Rat
Isotype	Rabbit Ig
Calculated MW	81545
Antigen Region	442-471
Antigen Source	HUMAN
Target/Specificity	This PIK3R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-471 amino acids from human PIK3R2.
NCBI Accession	NP_005018.1

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Menge: 400 ul

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