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WEE1 Antibody (Center)

WEE1 Antibody (Center)

ArtNr	ABC-AP8106c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Wee1-like protein kinase, Wee1A kinase, WEE1, WEE1hu
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Primary Accession	P30291
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
Bio References	Kawasaki, H., et al., Oncogene 22(44):6839-6844 (2003). Hashimoto, O., et al., Mol. Carcinog. 36(4):171-182 (2003). Yuan, H., et al., J. Virol. 77(3):2063-2070 (2003). Masaki, T., et al., Hepatology 37(3):534-543 (2003). de Noronha, C.M., et al., Science 294(5544):1105-1108 (2001).
Clonality	Polyclonal
Clone/Animal Names	RB3524
Gene ID	7465
Gene Name	WEE1
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Anti-WEE1 Antibody (A159) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 72 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	71597
Antigen Region	144-173
Antigen Source	HUMAN
Target/Specificity	This WEE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the Central region of human WEE1.
NCBI Accession	NP_001137448.1; NP_003381.1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AP8106c-datasheet.pdf

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Menge: 400 ul

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