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ABI1 Antibody (N-term)

ABI1 Antibody (N-term)

ArtNr	ABC-AP8535A
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Abi-1, ABI1, Spectrin SH3 domain-binding protein 1, Eps8 SH3 domain-binding protein, Eps8-binding protein, e3B1, Nap1-binding protein, Nap1BP, Abl-binding protein 4, AblBP4, SSH3BP1, Abelson interactor 1, Abl interactor 1
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Primary Accession	Q8IZP0
Antigen Type	Synthetic Peptide
Application	IF, FC, IHC-P, WB
Bio Background	ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, this protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling.
Bio References	Wang, C., et.al., Mol. Cancer Res. 5 (10), 1031-1039 (2007) Carabeo, R.A., et.al., Cell. Microbiol. 9 (9), 2278-2288 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB22014
Gene ID	10006
Gene Name	ABI1 (HGNC:11320)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Immunofluorescence analysis of ABI1 Antibody (N-term) with paraffin-embedded human brain tissue . 0.05 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of ABI1 Antibody (N-term) (Cat. #AP8535a) in MCF-7, CEM, Jurkat cell line lysates (35ug/lane). ABI1 (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human brain tissue reacted with ABI1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Legend image 4	Flow cytometric analysis of SK-Br-3 cells using ABI1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	P62484; Q9NYB9; Q9QZM5; Q8CBW3; F1R187
Predicted	Zf, M, Rat
Isotype	Rabbit Ig
Calculated MW	55081
Antigen Region	81-108
Antigen Source	HUMAN
Target/Specificity	This ABI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human ABI1.
NCBI Accession	NP_001012768.1; NP_001012769.1; NP_001012770.1; NP_001171587.1; NP_001171590.1; NP_001171591.1; NP_001171592.1; NP_001171593.1; NP_001171594.1; NP_001171595.1; NP_001171596.1; NP_005461.2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-AP8535A-datasheet.pdf

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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