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ABI1 Antibody (N-term)

ABI1 Antibody (N-term)

Item no.	ABC-AP8535A
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, FC, IF, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Abi-1, ABI1, Spectrin SH3 domain-binding protein 1, Eps8 SH3 domain-binding protein, Eps8-binding protein, e3B1, Nap1-binding protein, Nap1BP, Abl-binding protein 4, AblBP4, SSH3BP1, Abelson interactor 1, Abl interactor 1
Available
Primary Accession	Q8IZP0
Antigen Type	Synthetic Peptide
Application	IF, FC, IHC-P, WB
Bio Background	ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, this protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling.
Bio References	Wang, C., et.al., Mol. Cancer Res. 5 (10), 1031-1039 (2007) Carabeo, R.A., et.al., Cell. Microbiol. 9 (9), 2278-2288 (2007)
Clonality	Polyclonal
Clone/Animal Names	RB22014
Gene ID	10006
Gene Name	ABI1 (HGNC:11320)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Immunofluorescence analysis of ABI1 Antibody (N-term) with paraffin-embedded human brain tissue . 0.05 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.
Type image 1	IF
Dilution image 1	1:10~50
Legend image 2	Western blot analysis of ABI1 Antibody (N-term) (Cat. #AP8535a) in MCF-7, CEM, Jurkat cell line lysates (35ug/lane). ABI1 (arrow) was detected using the purified Pab.
Type image 2	WB
Dilution image 2	1:1000
Legend image 3	Formalin-fixed and paraffin-embedded human brain tissue reacted with ABI1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 3	IHC-P
Dilution image 3	1:50~100
Legend image 4	Flow cytometric analysis of SK-Br-3 cells using ABI1 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 4	FC
Dilution image 4	1:10~50
Other Accession	P62484; Q9NYB9; Q9QZM5; Q8CBW3; F1R187
Predicted	Zf, M, Rat
Isotype	Rabbit Ig
Calculated MW	55081
Antigen Region	81-108
Antigen Source	HUMAN
Target/Specificity	This ABI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human ABI1.
NCBI Accession	NP_001012768.1; NP_001012769.1; NP_001012770.1; NP_001171587.1; NP_001171590.1; NP_001171591.1; NP_001171592.1; NP_001171593.1; NP_001171594.1; NP_001171595.1; NP_001171596.1; NP_005461.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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