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Biotinylated Human ASGR1 / ASGPR1 Protein, His,Avitag™ Europäischer Partner

ArtNr GS1-H82Q3-200ug
Hersteller ACROBiosystems
Menge 200 ug
Quantity options 200 ug 25 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Biotin, Avi
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias ASGP-R 1,ASGPR 1,C-type lectin domain family 4 member H1,Hepatic lectin H1,HL-1
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
N-10xHis & N-Avi, Biotin-labeled
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
33.4 kDa
Manufacturer - Format
Powder
Description
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
Background
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2). ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
Molecule
ASGR1
Exp Region
Gln 62 - Leu 291
Characteristics
This protein carries a polyhistidine tag at the N-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 33.4 kDa. The protein migrates as 40-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, 0.2 M Arginine, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ug
Lieferbar: In stock
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