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Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (MALS verified)

Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag (MALS verified)

ArtNr	HE2-H5254-1mg
Hersteller	ACROBiosystems
Menge	500 ug x 2
Quantity options	100 ug 500 ug x 2
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, Fc
Purity	90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-Fc \| C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	95.9 kDa & 94.9 kDa
Manufacturer - Format	Powder
Description	The Human Epidermal Growth Factor Receptor 2 (HER2) and HER3 form a potent pro-oncogenic heterocomplex upon binding of growth factor neuregulin-1β (NRG1β). The HER2/HER3 extracellular dimer dynamics likely have important implications for modulating receptor activity.
Background	The Human Epidermal Growth Factor Receptor 2 (HER2) and HER3 form a potent pro-oncogenic heterocomplex upon binding of growth factor neuregulin-1β (NRG1β). The HER2/HER3 extracellular dimer dynamics likely have important implications for modulating receptor activity.
Molecule	Her2 & ErbB3
Exp Region	Thr 23 - Thr 652 & Ser 20 - Thr 643
Characteristics	Human Her2 & ErbB3 Protein, Fc Tag&Fc Tag, produced by co-expression of HER2 and ErbB3, has a calculated MW of 95.9 kDa (HER2) and 94.9 kDa (ErbB3). Subunit HER2 is fused with a human IgG1 Fc fragment at the C-terminus and subunit ErbB3 is fused with a human IgG1 Fc fragment at the C-terminus. The protein migrates as 110-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

HE2-H5254-1mg-datasheet.pdf

HE2-H5254-1mg-safety-datasheet.pdf