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Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (Monomer, MALS verified)

Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (Monomer, MALS verified)

ArtNr	HLD-H52H4-25ug
Hersteller	ACROBiosystems
Menge	25 ug
Quantity options	200 ug 25 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	90%
Formula	PBS, pH7.4
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	C-10xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	36.0 kDa and 11.7 kDa
Manufacturer - Format	Powder
Description	Human HLA-A11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (HLD-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A11:01) & Ile 21 - Met 119 (B2M) & VVGADGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVGADGVGK).
Background	The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A1101 KRASG12D (VVGADGVGK) complex protein is a complex of HLA-A1101 of the MHC Class I, B2M, and VVGADGVGK peptide of the KRASG12D.
Molecule	HLA-A*1101 \| B2M \| KRASG12D (VVGADGVGK)
Exp Region	Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGADGVGK peptide
Characteristics	Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12D peptide.This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 41-45 kDa and 14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

HLD-H52H4-25ug-datasheet.pdf

HLD-H52H4-25ug-safety-datasheet.pdf