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Etilefrine (hydrochloride) (Standard) Europäischer Partner

ArtNr HY-A0144AR
Hersteller MedChem Express
CAS-Nr. 943-17-9
Menge 1 ea
Quantity options 1 ea 100 mg 10 mg 25 mg 50 mg
Kategorie
Typ Standard
Specific against other
Citations [1]Chi Xu, et al. Accurate Drug Repositioning through Non-tissue-Specific Core Signatures from Cancer Transcriptomes. Cell Rep. 2018 Oct 9;25(2):523-535.e5.|[2]R Yamazaki, et al. Effects of dihydroergotamine and Etilefrine on experimentally-induced postural hypotension in dogs. J Pharmacobiodyn. 1990 Sep;13(9):519-24.|[3]Adigun SA, et al. A comparison of the effects of salbutamol, etilefrine and dextran during hypotension and low cardiac output states in rabbit. Clin Exp Pharmacol Physiol. 1984 Nov-Dec;11(6):627-43.
Smiles OC(CNCC)C1=CC=CC(O)=C1.[H]Cl
ECLASS 10.1 42021590
ECLASS 11.0 42021590
UNSPSC 12352202
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Reference Standards
Manufacturer - Targets
Adrenergic Receptor; Akt; AMPK; Reference Standards
Shipping Temperature
Room temperature
Molecular Weight
217.696
Product Description
Etilefrine hydrochloride (Standard) is the analytical standard of Etilefrine hydrochloride (HY-A0144A). This product is intended for research and analytical applications. Etilefrine hydrochloride is a sympathetic nerve agonist and AMPK activator that selectively targets α1/β1 adrenergic receptors. Etilefrine hydrochloride stimulates α1 adrenergic receptors, leading to contraction of vascular smooth muscle and increased peripheral resistance. Etilefrine hydrochloride also stimulates β1 receptors to enhance myocardial contractility and increase heart rate, thereby increasing blood pressure and improving cardiac output. Etilefrine hydrochloride also bidirectionally regulates the AMPK/Akt pathway and modulates the phosphorylation levels. Etilefrine hydrochloride can be used in cardiovascular research, such as postural hypotension, chylothorax, and improving low cardiac output[1][2][3].
Manufacturer - Research Area
Cardiovascular Disease
Manufacturer - Pathway
Epigenetics; GPCR/G Protein; Neuronal Signaling; Others; PI3K/Akt/mTOR
Isoform
α adrenergic receptor; β adrenergic receptor

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 ea
Lieferbar: In stock
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