Sulfapyridine

ArtNr	HY-B0212-10g
Hersteller	MedChem Express
CAS-Nr.	144-83-2
Menge	10 g
Quantity options	10 g 10 mM/1 mL 1 g 500 mg 5 g
Kategorie	Oncology Food Safety Antibiotics Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer Testicular & Prostate Cancer
Typ	Inhibitors
Specific against	other
Purity	99.85
Citations	[1]Kazuki Omoteyama, et al. Effects of salazosulfapyridine on the profile of cell surface proteins, revealed by biotinylation of cell surface proteins and 2-dimentional electrophoresis. Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):47-56.\|[2]J J Andreasen, et al. In vitro susceptibility of diarrhoea producing gram negative enteric bacteria to sulfasalazine, 5-aminosalicylic acid, sulfapyridine and four quinolones. Brief report. APMIS. 1988 Jun;96(6):568-70.\|[3]Y L Hong, et al. Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39(8):1756-63.\|[4]H M Kim, et al. Inhibitory effect of mast cell-mediated immediate-type allergic reactions by sulfapyridine. Immunopharmacol Immunotoxicol. 2000 May;22(2):253-66.
Smiles	O=S(C1=CC=C(N)C=C1)(NC2=NC=CC=C2)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	249.29
Product Description	Sulfapyridine, a major metabolite of Sulfasalazine, is a sulfonamide antibiotic agent. Sulfapyridine inhibits recombinant P. carinii dihydropteroate synthetase (DHPS) with an IC50 of 0.18 μM. Sulfapyridine has antibacterial, anti-inflammatory and anti-rheumatic activities[1][2][3].
Manufacturer - Research Area	Infection; Inflammation/Immunology
Solubility	DMSO: 60 mg/mL (ultrasonic)\|H2O: < 0.1 mg/mL
Manufacturer - Pathway	Anti-infection
Clinical information	Launched

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