Ethinylestradiol

ArtNr	HY-B0216-5g
Hersteller	MedChem Express
CAS-Nr.	57-63-6
Menge	5 g
Quantity options	100 mg 10 mM/1 mL 1 g 500 mg 5 g
Kategorie	Oncology Food Safety Hormones Inhibitors & Compound Libraries Small Molecules By Organ Uterine, Ovarian & Cervical Cancer
Typ	Inhibitors
Specific against	other
Purity	99.96
Citations	[1]Arnal J F, et al. Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production[J]. Proceedings of the National Academy of Sciences, 1996, 93(9): 4108-4113. \|[2]Notch EG, et al. 17alpha-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells. Aquat Toxicol. 2009 Dec 13;95(4):273-8.\|[3]Bertolotti M, et al. Effect of hypocholesterolemic doses of 17 alpha-ethinyl estradiol on cholesterol balance in liver and extrahepatic tissues. J Lipid Res. 1996 Aug;37(8):1812-22. \|[4]Mandrup KR, et al. Effects of perinatal ethinyl estradiol exposure in male and female Wistar rats. Reprod Toxicol. 2013 Dec;42:180-91. \|[5]Kuhl H. Pharmacology of estrogens and progestogens: influence of different routes of administration. Climacteric. 2005 Aug;8 Suppl 1:3-63.
Smiles	OC1=CC=C2C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4(C#C)O)=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Ethynyl estradiol,17α-Ethynylestradiol
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Endogenous Metabolite; Estrogen Receptor/ERR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	296.40
Product Description	Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers[1].
Manufacturer - Research Area	Endocrinology; Cancer
Solubility	DMSO: ≥ 100 mg/mL\|Ethanol: ≥ 100 mg/mL\|H2O: < 0.1 mg/mL (ultrasonic; warming; heat to 80°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Clinical information	Launched

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