Lomefloxacin (hydrochloride)

Reference compound

Antibiotic; Apoptosis; Bacterial; Reactive Oxygen Species (ROS); Topoisomerase

4°C (Powder, sealed storage, away from moisture and light)

Lomefloxacin hydrochloride (NY-198 hydrochloride) is an orally active difluoroquinolone antibiotic. Lomefloxacin hydrochloride prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II. Lomefloxacin hydrochloride induces ROS production and Apoptosis. Lomefloxacin hydrochloride has broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin hydrochloride has anticancer effects against melanoma. Lomefloxacin hydrochloride can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin and melanoma [1][2][3][4][5][6].

H2O : 7.14 mg/mL (ultrasonic; warming; heat to 60°C)

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