Insulin R/CD220, Human (HEK293, C-His)

Recombinant Proteins

Stored at -20°C for 2 years

The insulin R/CD220 protein is a receptor tyrosine kinase that coordinates insulin action by phosphorylating substrates such as IRS and SHC upon insulin binding. Phosphorylated IRS activates PI3K-AKT/PKB to exert metabolic effects, and activates Ras-MAPK to promote growth and differentiation. Insulin R/CD220 Protein, Human (HEK293, C-His) is the recombinant human-derived Insulin R/CD220 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Insulin R/CD220 Protein, Human (HEK293, C-His) is 929 a.a., with molecular weight of ~130 kDa.