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Nivolumab Biosimilar - Research Grade

Nivolumab Biosimilar - Research Grade

ArtNr	ICH4009-200mg
Hersteller	IchorBio
Menge	200 mg
Specific against	Human (Homo sapiens)
Isotype	IgG4 Kappa
Purity	>95% by SDS-PAGE and HPLC
Citations	Narsimhan et al. Mobile Affinity Selection Chromatography Analysis of Therapeutic Monoclonal Antibodies. Analytical Chemistry
Alias	Programmed cell death protein 1, Pdcd1, CD279
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Low endotoxin, Biosimilar, recombinant antibody
Manufacturer - Isotype	IgG4 kappa
Manufacturer - Targets	PD-1
Manufacturer - Host	Humanized
Shipping Temperature	Blue ice
Storage Conditions	Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation	Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Background	Nivolumab biosimilar is a human monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin that has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line.
Concentration	1.0 - 5.0 mg/ml
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity	Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Nivolumab.
Purification method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control	Bulk Human IgG4 Isotype Control (IB4) [ICH2257]
Buffer	ICH3001-100ml, ICH3002-100ml, ICH3003-100ml

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ICH4009-200mg-datasheet.pdf

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 200 mg

lieferbar

Lieferung vsl. bis 19.06.2025

Express-Lieferung: 1 Tage sparen

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