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Rat IL-23 R Protein, His Tag (MALS verified)

Rat IL-23 R Protein, His Tag (MALS verified)

ArtNr	ILR-R52H3-200ug
Hersteller	ACROBiosystems
Menge	200 ug
Format	Solid
Specific against	Rat (Rattus norvegicus)
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	95%
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10×His, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	39.6 kDa
Description	Rat IL-23 R Protein, His Tag (ILR-R52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 39 - Asp 367 (Accession # F1LX96).
Background	Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Molecule	IL-23R
Exp Region	Gly 39 - Asp 367
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.6 kDa. The protein migrates as 50-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

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Menge: 200 ug

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Lieferung vsl. bis 19.06.2025

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