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Rat IL-23 R Protein, His Tag (MALS verified)

Rat IL-23 R Protein, His Tag (MALS verified)

Item no.	ILR-R52H3-200ug
Manufacturer	ACROBiosystems
Amount	200 ug
Format	Solid
Specific against	Rat (Rattus norvegicus)
Host	HEK293
Conjugate/Tag	Unconjugated, HIS
Purity	95%
Shipping condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-10×His, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	39.6 kDa
Description	Rat IL-23 R Protein, His Tag (ILR-R52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 39 - Asp 367 (Accession # F1LX96).
Background	Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Molecule	IL-23R
Exp Region	Gly 39 - Asp 367
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.6 kDa. The protein migrates as 50-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200 ug

available

Delivery expected until 6/19/2025