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Ibuprofen-d3 (sodium)

Ibuprofen-d3 (sodium)

ArtNr	HY-78131CS-10mg
Hersteller	MedChem Express
CAS-Nr.	1219805-09-0
Menge	10 mg
Quantity options	10 mg 1 ea 1 mg 5 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitor
Specific against	other
Purity	99.0
Citations	[1]Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. \|[2]Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36(5):3237-43. \|[3]Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. \|[4]M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141(1):186-92.
Smiles	O=C(O[Na])C(C([2H])([2H])[2H])C1=CC=C(CC(C)C)C=C1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	(±)-Ibuprofen-d3 (sodium)
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Apoptosis; COX; Isotope-Labeled Compounds; Parasite
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	231.28
Product Description	Ibuprofen-d3 ((±)-Ibuprofen-d3) sodium is the deuterium labeled Ibuprofen sodium (HY-78131C). Ibuprofen sodium is an orally active, selective COX-1 inhibitor with an IC50 value of 13 μM. Ibuprofen sodium inhibits cell proliferation, angiogenesis, and induces cell apoptosis. Ibuprofen sodium is a nonsteroidal anti-inflammatory agent and a nitric oxide (NO) donor. Ibuprofen sodium can be used in the research of pain, swelling, inflammation, infection, immunology, cancers[1][2][3][4].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology; Neurological Disease
Solubility	10 mM in DMSO\|DMF: ≥ 30mg/mL\|DMSO: ≥ 50mg/mL\|Ethanol: ≥ 50mg/mL
Manufacturer - Pathway	Anti-infection; Apoptosis; Immunology/Inflammation; Others
Clinical information	No Development Reported

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HY-78131CS-10mg-safety-datasheet.pdf