Chlorphenoxamine

ArtNr	HY-B1607-5mg
Hersteller	MedChem Express
CAS-Nr.	77-38-3
Menge	5 mg
Quantity options	10 mM/1 mL 10 mg 50 mg 5 mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.20
Citations	[1]Ashraf A, et al. Novel RP-HPLC-DAD approach for simultaneous determination of chlorphenoxamine hydrochloride and caffeine with their related substances. BMC Chem. 2024;18(1):133. Published 2024 Jul 19.\|[2]Ashraf A, et al. Smart green spectrophotometric estimation and content uniformity testing of chlorphenoxamine HCl and caffeine in bulk forms and combined pharmaceutical formulation. Sci Rep. 2025;15(1):9482. Published 2025 Mar 19.\|[3]BAZEX A, et al. Trial treatment of urticaria with chlorphenoxamine. Clinique (Paris). 1963 Jul-Aug;58:447-50.\|[4]ULDALL PR, et al. Chlorphenoxamine hydrochloride in parkinsonism. A controlled trial. Br Med J. 1961 Jun 10;1(5240):1649-52.\|[5]Schafer A, et al. Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics. Antiviral Res. 2018 Sep;157:47-56.
Smiles	CN(CCOC(C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)C)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neurodegeneration
Manufacturer - Category	Reference compound / Active compounds; API
Manufacturer - Targets	Filovirus; Histamine Receptor; Parasite; SARS-CoV
Manufacturer - HS Code	H302, H315, H319, H335
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	303.83
Product Description	Chlorphenoxamine, an antihistamine and anticholinergic agent is a GPCR antagonist. Chlorphenoxamine inhibits multiple lethal viral diseases, such as SARS-CoV, MERS-CoV, EBOV and malaria. Chlorphenoxamine shows anti-filovirus activity against both EBOV and Marburg virus (MARV) with IC50s of 1.1 μM and 6.2 μM, respectively. Chlorphenoxamine is used for allergic conditions, urticaria, viral diseases and Parkinson’s disease[1][2][3][4][5].
Manufacturer - Research Area	Infection; Inflammation/Immunology; Neurological Disease
Solubility	DMSO : ≥ 48 mg/mL
Manufacturer - Pathway	Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Clinical information	Launched
UNSPSC Code	12352005
Precautionary	H302, H315, H319, H335

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