« Zurück
Startseite /
IL-6R, Canine (HEK293, His)

IL-6R, Canine (HEK293, His)

ArtNr	HY-P73221-20ug
Hersteller	MedChem Express
Menge	20 ug
Quantity options	100 ug 10 ug 20 ug 2 ug 50 ug 5 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Purity	96.50
Dry ice	Yes
Sequence	LAPWGCPAPE VMSGVVTSLP GASVTLTCPG GEPEDNGTVQ WLLQNLVDDS YLGSRAAVGR TLLLRSVQLS DSGNYSCYQD GRLAGTVRLL VDAPPEEPQL ACFRKSPLSM VFCEWSPRHP PSPKTRATLL VRKFRGRPVG DSQEPCPYAQ GPQKFSCQLA VPEGDNSLYV VSLCVTNSAG SRSSTPQTFE GYGILQPDPP VNITVTAVDR NPRWLRVSWQ DPPSWNSYFY RL
Citations	[1]Garbers C, et al. Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor. J Biol Chem. 2011 Dec 16;286(50):42959-70.\|[2]Malemud, et al. Defective JAK-STAT Pathway Signaling Contributes to Autoimmune Diseases. Curr Pharmacol Rep 4, 358-366.\|[3]Larsen JV, et al. SorLA in Interleukin-6 Signaling and Turnover. Mol Cell Biol. 2017 May 16;37(11):e00641-16.\|[4]Kang S, et al. Targeting Interleukin-6 Signaling in Clinic. Immunity. 2019 Apr 16;50(4):1007-1023.\|[5]Giannitrapani L, et al. Circulating IL-6 and sIL-6R in patients with hepatocellular carcinoma. Ann N Y Acad Sci. 2002 Jun;963:46-52.\|[6]Arnold P, et al. Joint Reconstituted Signaling of the IL-6 Receptor via Extracellular Vesicles. Cells. 2020 May 24;9(5):1307.\|[7]Mishra AK, et al. Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells. Leukemia. 2019 Nov;33(11):2695-2709.\|[8]Gruber CN, et al. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020 Nov 12;183(4):982-995.e14.
Smiles	LAPWGCPAPE VMSGVVTSLP GASVTLTCPG GEPEDNGTVQ WLLQNLVDDS YLGSRAAVGR TLLLRSVQLS DSGNYSCYQD GRLAGTVRLL VDAPPEEPQL ACFRKSPLSM VFCEWSPRHP PSPKTRATLL VRKFRGRPVG DSQEPCPYAQ GPQKFSCQLA VPEGDNSLYV VSLCVTNSAG SRSSTPQTFE GYGILQPDPP VNITVTAVDR NPRWLRVSWQ DPPSWNSYFY RLQFELRYRA ERSKTFTMLM IKEFQHHCII HDAWRGMRHV VQLRAREEFG HGSWSTWSQE AVGTPWTESR SPAAETELPH STQAPTTNED NKNNISKDIA NATSLPVQDS SSAPLP
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-6R Protein,Canine (HEK293,His),Canine,HEK293
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Dry Ice
Storage Conditions	Stored at -80°C for 1 year
Molecular Weight	Approximately 39.8 kDa
Product Description	IL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway[1][2]. IL-6R alpha, Canine consists of 462 amino acids (M1-R462) and is produced in HEK293 cells with a C-Terminal His-tag.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 20 ug

lieferbar

Technische Frage stellen