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Crocin II Europäischer Partner

ArtNr TMO-T3779-200mg
Hersteller TargetMol
CAS-Nr. 55750-84-0
Menge 200 mg
Quantity options 100 mg 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Kategorie
Typ Inhibitors
Specific against other
Purity 0,9919
Formula C38H54O19
Smiles C\C(\C=C\C=C(/C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)=C/C=C/C=C(\C)/C=C/C=C(\C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Targets
COX|||Caspase|||NO Synthase
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
814.82
Description
Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin II can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin II has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, Crocin II , can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.
Pathways
Apoptosis|||Neuroscience|||Proteases/Proteasome|||Immunology/Inflammation
Bioactivity
Crocin has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expression of iNOS and caspase-3. Crocin can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite. Crocin has antihyperlipidemic effect, may be due to the inhibition of pancreatic lipase and crocin, and its metabolite, crocetin, can improve hyperlipidemia. Crocin has antidepressant effects by increasing CREB, BDNF and VGF levels in hippocampus.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 mg
Lieferbar: In stock
lieferbar

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