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TrkB (NTRK2) Mouse Monoclonal Antibody [Clone ID: LBI2E1]

ArtNr LBI-AMM09066VCF
Hersteller Leading Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Clon LBI2E1
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GP145-TrkB, OBHD, trk-B, TRKB
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
NTRK2
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
MAPK signaling pathway, Neurotrophin signaling pathway
Overview
Carrier-free (BSA/glycerol-free) NTRK2 mouse monoclonal antibody, clone LBI2E1
Immunogen
Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector
Gene Name
Homo sapiens neurotrophic receptor tyrosine kinase 2 (NTRK2), transcript variant b, mRNA.
Symbol
NTRK2
Function
Druggable Genome, Protein Kinase, Transmembrane
Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:1000, IHC 1:150, IF 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
MAPK signaling pathway, Neurotrophin signaling pathway

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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