Comparison

TrkB (NTRK2) Mouse Monoclonal Antibody [Clone ID: LBI2E1]

Item no. LBI-AMM09066VCF
Manufacturer Leading Biology
Amount 100 ug
Category
Type Antibody Monoclonal
Format Lyophilized
Clone LBI2E1
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Conjugate/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GP145-TrkB, OBHD, trk-B, TRKB
Available
Manufacturer - Category
mAbs-V
Manufacturer - Targets
NTRK2
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
MAPK signaling pathway, Neurotrophin signaling pathway
Overview
Carrier-free (BSA/glycerol-free) NTRK2 mouse monoclonal antibody, clone LBI2E1
Immunogen
Full-length protein expressed in 293T cell transfected with human NTRK2 expression vector
Gene Name
Homo sapiens neurotrophic receptor tyrosine kinase 2 (NTRK2), transcript variant b, mRNA.
Symbol
NTRK2
Function
Druggable Genome, Protein Kinase, Transmembrane
Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:1000, IHC 1:150, IF 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
MAPK signaling pathway, Neurotrophin signaling pathway

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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