Vergleich

XRCC1 Mouse Monoclonal Antibody [Clone ID: LBI2E8]

ArtNr LBI-AMM09513VCF
Hersteller Leading Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Clon LBI2E8
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias RCC
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
XRCC1
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Base excision repair
Overview
Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone LBI2E8
Immunogen
Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Gene Name
Homo sapiens X-ray repair cross complementing 1 (XRCC1), mRNA.
Symbol
XRCC1
Function
Druggable Genome
Summary
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:2000, IF 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Base excision repair

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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