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XRCC1 Mouse Monoclonal Antibody [Clone ID: LBI2E8]

XRCC1 Mouse Monoclonal Antibody [Clone ID: LBI2E8]

Item no.	LBI-AMM09513VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Lymphoma Sarcoma Adenocarcinoma By Organ Renal Cancer
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI2E8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	RCC
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	XRCC1
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Base excision repair
Overview	Carrier-free (BSA/glycerol-free) XRCC1 mouse monoclonal antibody, clone LBI2E8
Immunogen	Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.
Gene Name	Homo sapiens X-ray repair cross complementing 1 (XRCC1), mRNA.
Symbol	XRCC1
Function	Druggable Genome
Summary	The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:2000, IF 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Base excision repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/15/2026

Express Delivery: Save 17 days

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