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Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]

ArtNr LBI-AMM15058VCF
Hersteller Leading Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Clon LBI1F3
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
TYR
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism
Overview
Carrier-free (BSA/glycerol-free) TYR mouse monoclonal antibody, clone LBI1F3
Immunogen
Human recombinant protein fragment corresponding to amino acids 19-320 of human TYR (NP_000363) produced in E.coli.
Gene Name
Homo sapiens tyrosinase (TYR), mRNA.
Symbol
TYR
Function
Transmembrane
Summary
The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:2000, IHC 1:150
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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