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Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]

Tyrosinase (TYR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]

Item no.	LBI-AMM15058VCF
Manufacturer	Leading Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Melanoma
Type	Antibody Monoclonal
Format	Lyophilized
Clone	LBI1F3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Conjugate/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
Available
Manufacturer - Category	mAbs-V
Manufacturer - Targets	TYR
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism
Overview	Carrier-free (BSA/glycerol-free) TYR mouse monoclonal antibody, clone LBI1F3
Immunogen	Human recombinant protein fragment corresponding to amino acids 19-320 of human TYR (NP_000363) produced in E.coli.
Gene Name	Homo sapiens tyrosinase (TYR), mRNA.
Symbol	TYR
Function	Transmembrane
Summary	The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Melanogenesis, Metabolic pathways, Riboflavin metabolism, Tyrosine metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/20/2025

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