TNF-α Rabbit pAb (APR18490N)

pAbs-N

Calculated MW: 25kDaObserved MW: 28KDa

A synthetic peptide of human TNF

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.

Affinity purification