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RAB27A Antibody [AMM07444G]

RAB27A Antibody [AMM07444G]

ArtNr	LBI-AMM07444G
Hersteller	Leading Biology
Menge	100 ul
Quantity options	100 ul
Kategorie	Antibodies Cell Biology Cytoskeleton Flow Cytometry Western Blot ELISA Primary Antibodies small GTPases Rab Subfamily
Typ	Antibody Monoclonal
Applikationen	WB, FC
Clon	1590CT813.266.26
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ras-related protein Rab-27A, Rab-27, GTP-binding protein Ram, RAB27A, RAB27
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Manufacturer - Type	Monoclonal Antibodies
Manufacturer - Category	Abs-G
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	24868
Overview	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality RAB27A Antibody [AMM07444G].
Manufacturer - Specificity	This RAB27A antibody is generated from a mouse immunized with a recombinant protein of human RAB27A.
Cellular localization	Membrane; Lipid-anchor. Melanosome. Late endosome. Lysosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). Localizes to endosomal exocytic vesicles (PubMed:17237785).
Gene Name	RAB27A
Function	Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion (PubMed:30771381). Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
Summary	Tissue Location: Found in all the examined tissues except in brain. Low expression was found in thymus, kidney, muscle and placenta Detected in melanocytes, and in most tumor cell lines examined Expressed in cytotoxic T-lymphocytes (CTL) and mast cells
Dilution	FC-1:25WB-1:2000
Clonality	Monoclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 18.09.2025

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