Anti-CaMKII Antibody (56370) - 50 µg

Antibody Products>Neuroscience and Signal Transduction Antibodies|Products

Next Day 2 - 8°C

Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimer's disease, Angelman syndrome, and heart arrhythmia.

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