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Anti-Mouse Alpha Synuclein Mouse Monoclonal Antibody (56626) - 100 µg

ArtNr LEIN-56626-100ug
Hersteller Leinco Technologies
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Applikationen WB, IF, IHC, ICC, ELISA
Clon 3F8
Specific against other
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
ELISA, IHC, WB, DB, ICC/IF
Manufacturer - Category
Antibody Products>Heat Shock and Stress Protein Antibodies|Products
Manufacturer - Targets
Alpha Synuclein
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.
Product Description
Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals (1). Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus (2). Functionally, it has been shown to significantly interact with tubulin (3), and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory (4). SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson's disease. Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin (5, 6).
Manufacturer - Research Area
Neuroscience, Alzheimer's Disease, Neurodegeneration, Parkinson's Disease, Synuclein, Tangles & Tau
Concentration
1 mg/mL
Formulation
PBS pH 7.4, 50% glycerol, 0.09% Sodium azide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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