Anti-Human CCR8 (EL) - 20 µg

Primary Monoclonal Antibodies>Infectious Diseases

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CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and mouse CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

Polyclonal Antibody, CC Chemokine Receptor-8, TER1, CKR-L1, Chem R1, CCR8, Human, Anti-Human CCR8 (EL), CCR8 Antibody, CY6, TER1, CCR-8, CKRL1, CDw198, CMKBR8, GPRCY6, CMKBRL2, CC-CKR-8