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Anti-Mouse CD127 (IL-7Rα) [Clone A7R34] — Purified <i>in vivo </i>GOLD™ Functional Grade - 5 mg

ArtNr LEIN-C2223-5.0mg
Hersteller Leinco Technologies
Menge 5 mg
Quantity options 0.5 mg 1 mg 5 mg
Kategorie
Typ Antibody Monoclonal
Applikationen WB, FC, IF, IP, IHC, FA, other, IV
Clon A7R34
Specific against other
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
B, CyTOF®, FA, FC, IF Staining, IHC FF, in vivo, IP, WB
Manufacturer - Category
Purified in vivo Functional Grade>Gold Purified Bulk Antibodies|Purified in vivo Functional Grade|Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets
CD127
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Product Description
CD127 (IL7R-α) is a 60-90 kD type I cytokine receptor involved in the regulation of lymphopoiesis. The active receptor is an α/γ chain heterodimer. The common γ chain, which also associates with the IL-2 receptor, serves mainly to activate signal transduction via the IL7R complex. CD127 also interacts with the Thymic Stromal Lymphopoietin Receptor (TSLPR). CD127 determines signaling events via its association with cytoplasmic signaling molecules and has been reported to be a useful marker for identifying memory and effector T cells.
Manufacturer - Research Area
Immunology
Concentration
≥ 5.0 mg/ml
Formulation
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Antigen Distribution
IL-7Rα is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, NK-cells, naïve T cells, memory CD4+ and CD8+ T cells, intestinal colorectal and renal carcinoma cell lines, and keratinocytes.
Keywords
Monoclonal Antibody, CD127, IL-7Rα, Interleukin-7 receptor alpha, IL-7Rα chain, A7R34, Mouse, Anti-Mouse CD127 (IL-7Rα) - Purified Low Endotoxin Functional Formulation, Flow Cytometry, Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunology, thymocytes, IL-2, IL-4, IL-9, IL-13, IL-15, CD127 antigen, CD127, CD127ILRA, CDW127, IL-7 R alpha, IL-7 receptor subunit alpha, IL7R alpha, IL-7R subunit alpha, IL7R, IL7RA, IL-7Ra, IL-7R-alpha, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin 7 receptor, interleukin-7 receptor subunit alpha

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 mg
Lieferbar: In stock
lieferbar

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