Anti-Human IL-21R (Extracellular Domain) - 20 µg

Polyclonal Antibodies>Growth Factors & Cytokines

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Interleukin 21 receptor (IL-21R) is a novel member of the class-I-cytokine-receptor family and is selectively expressed in lymphoid tissues. IL21R shows strong sequence homologies to the interleukin-4 receptor alpha chain gene (IL4RA).1 IL-21R is an important amplifier of alternative macrophage activation. Collectively, these results illustrate an essential function for the IL-21R in the development of pathogen-induced Th2 responses, which may have relevance in therapies for both inflammatory and chronic fibrotic diseases.2 IL-21/IL-21R system may represent a new target for the treatment of Adult T-cell leukaemia (ATL).3

This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.

Polyclonal Antibody, Interleukin-21 Receptor, NILR, MGC10967, IL-21R, Human, Anti-Human IL-21R (Extracellular Domain)