ATM Monoclonal Antibody

This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze thaw cycles.

ATM; ATM; AT1; ATA; ATC; ATD; ATE; ATDC; TEL1; TELO1; MGC74674; DKFZp781A0353

Anti-ATM [Murine MAb recognizes full-length ATM, a 370 kDa nuclear phosphoprotein associated with cell cycle regulation and response to DNA repair.]
This antibody recognizes full-length ATM, a 370 kD nuclear phosphoprotein, which is involved in the autooal recessive disease ataxia telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation and response to DNA repair. The C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases). Its usefulness to monitor altered ATM expression in cancer is under active investigations.

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