Fumarate hydratase-IN-2 (sodium salt)

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 10mM*1mL (in DMSO)
ArtNr HY-100005A-10mM
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
Purity
>98%
MW
4404668
Formula
C25H25N2NaO4
Solubility
DMSO: 10.66 mg/mL
Biological Description
.Fumarate hydratase is an enzyme of the TCA cycle and cell-permeable inhibitors
(1) inhibition of fumarate hydratase can contribute to tumorigenicity in some cells.
(2) The use of a photoaffinity labeling strategy identified fumarate hydratase as the principal pharmacological target. Final biochemical studies confirmed dose-dependent, competitive inhibition of this enzyme
(3) Chemical inhibition of fumarate hydratase renders cells highly dependent on glucose metabolism for survival.
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 447,50 €
Preis: 447,50 €
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