BAPTA

ArtNr	HY-100168-10mM
Hersteller	MedChem Express
CAS-Nr.	85233-19-8
Menge	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 200 mg 500 mg
Kategorie	Cell Biology Cell Stainings Cardiovascular Research Ischemia & Reperfusion Injury Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	98.10
Citations	[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. \|[2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. \|[3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium Adv Sci (Weinh). 2021 May 27;e2100363.\|Aging. 2019 Nov 22;11(22):10385-10408.\|Biomed Pharmacother. 2023 Aug 25;166:115343.\|Biomed Pharmacother. 2023 May.\|bioRxiv. 2023 Jun 25.\|Cardiovasc Ther. 2023 Mar 30,22.\|Exp Neurol. 2023 Feb 13;363:114350.\|Free Radic Biol Med. 2024 Jan 6:S0891-5849(24)00002-9.\|J Cancer. 2024 Jan 1;15(2):343-355.\|J Cell Mol Med. 2020 Aug;24(16):9287-9299.\|J Clin Invest. 2024 Apr 25:e176355.\|J Ethnopharmacol. 2022: 115923.\|J Funct Foods. 2024 Oct.\|J Funct Foods. December 2021, 104791.\|J Ginseng Res. 10 August 2021.\|J Invest Dermatol. 2024 May 30:S0022-202X(24)00384-1.\|J Pharm Pharmacol. 2024 Jan 25:rgae002.\|J Pineal Res. 2024 Aug;76(5):e12987.\|J Thromb Haemost. 2021 Aug 19.\|Mil Med Res. 2023 Nov 25;10(1):56.\|Mol Med Rep. 2023 Nov 27.\|Sci Immunol. 2019 Jun 28;4(36):eaau6426.\|Sci Total Environ. 2020 Feb 10;703:134702.\|Toxicology. 2023 Nov 19:153674.\|Vet Microbiol. 2019 Dec;239:108498.\|Cell Signal. 2025 Mar 17:111753.
Smiles	O=C(O)CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	85233-19-8
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Biochemical Assay Reagents
Manufacturer - Targets	Phospholipase
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	476.43
Product Description	BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].
Manufacturer - Research Area	Others
Solubility	1M NaOH: 33.33 mg/mL (ultrasonic; adjust pH to 11 with NaOH)\|DMSO: 15.62 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-100168-10mM-safety-datasheet.pdf