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HIV-1 integrase inhibitor

HIV-1 integrase inhibitor

ArtNr	HY-13025-50mg
Hersteller	MedChem Express
CAS-Nr.	544467-07-4
Menge	50 mg
Quantity options	100 mg 10mM/1mL 10 mg 50 mg 5mg
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	96.37
Formula	C11H9N3O4
Citations	[1]Hobaika, Z.; Zargarian, L.; Maroun, R. G.; Mauffret, O.; Burke, T. R., Jr.; Fermandjian, S. HIV-1 Integrase and Virus and Cell DNAs: Complex Formation and Perturbation by Inhibitors of Integration. Neurochemical Research (2010), 35(6), 888-893.<br/>[2]Loizidou, Eriketi Z.; Zeinalipour-Yazdi, Constantinos D.; Christofides, Tasos; Kostrikis, Leondios G. Analysis of binding parameters of HIV-1 integrase inhibitors: Correlates of drug inhibition and resistance. Bioorganic & Medicinal Chemistry (2009), 17(13), 4806-4818.<br/>[3]Kawasuji T.Carbamoyl Pyridone HIV-1 Integrase Inhibitors. 1. Molecular Design and Establishment of an Advanced Two-Metal Binding Pharmacophore.J Med Chem. 2012 Sep 10.<br/>[4]Yan A, Xuan S, Hu X.Classification of Active and Weakly Active ST Inhibitors of HIV-1 Integrase Using a Support Vector Machine.Comb Chem High Throughput Screen. 2012 Aug 28.<br/>[5]Yu S, Zhao G.Development of Polyphenols as HIV-1 Integrase Inhibitors: A Summary and Perspective.Curr Med Chem. 2012 Aug 27.
Smiles	OC(/C(O)=C/C(C1=CC=CC(CN=[N+]=[N-])=C1)=O)=O
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	544467-07-4
Lieferbar
Product Description	HIV-1 integrase inhibitor is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-anti-virus
MolecularWeight	247.21
Clinical Information	No Development Reported
Manufacturers Research Area	Infection
Solubility	DMSO : ≥ 100 mg/mL
Target	HIV; HIV Integrase
Manufacturers Target	HIV; HIV Integrase
Isoform	HIV-1
Manufacturers Pathway	Anti-infection; Metabolic Enzyme/Protease
Manufacturers Product type	Reference compound

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HY-13025-50mg-safety-datasheet.pdf