c-Kit-IN-1

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 10mM*1mL (in DMSO)
ArtNr HY-15240-10mM
eClass 6.1 30220300
eClass 9.0 32160605
Lieferbar
CAS No.
1225278-16-9
Purity
>98%
MW
4894734
Formula
C26H21F2N5O3
Solubility
DMSO
Biological Description
c-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of <200 nM.

IC50 & Target: IC50: <200 nM (c-Met), <200 nM (c-Kit), <2 uM (KDR), <10 uM (PDGFRalpha), <10 uM (PDGFRbeta)[1]In Vitro: c-Kit-IN-1 is a c-Kit and c-Met inhibitor extracted from patent 2010051373A1, compound example 45, has an IC50 of <200 nM. c-Kit-IN-1 also inhibits KDR, PDGFR alpha and beta with IC50s of <2 uM, <10 uM and <10 uM, respectively[1].In Vivo:
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 384,29 €
Preis: 384,29 €
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