Eravacycline

ArtNr	HY-16980-5mg
Hersteller	MedChem Express
CAS-Nr.	1207283-85-9
Menge	5 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 5 mg
Kategorie	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Specific against	other
Citations	Ann Lab Med. 2021 May 1;41(3):293-301. Antibiotics (Basel). 2022, 11(10), 1298. Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19. Antimicrob Agents Chemother. 2021 May 18;65(6):e00203-21. Antimicrob Agents Chemother. 2024 Jan 30:e0112023. Clin Exp Pharmacol Physiol. 2023 Apr 22. Diagn Micr Infec Dis. 2020 Nov;98(3):115129. Infect Drug Resist. 2023 Apr 17. Infect Drug Resist. 2023 Sep 7. J Antibiot (Tokyo). 2019 Aug;72(8):600-604. J Antibiot (Tokyo). 2022 Jul 27. J Antimicrob Chemother. 2021 May 6;dkab141. J Clin Microbiol. 2020 Jan 28;58(2):e01603-19. Microbiol Spectr. 2022 Dec 8;e0323822. Microbiol Spectr. 2023 May 4;e0071823. Nat Microbiol. 2023 Mar;8(3):410-423. Nat Struct Mol Biol. 2023 Aug 7. Virulence. 2022 Dec;13(1):77-88. ACS Infect Dis. 2024 Nov 13. Biomaterials. 2024 Sep 11:314:122815. Cureus. 2024 Dec 1;16(12):e74917. J Antimicrob Chemother. 2021 Feb 11;76(3):653-658. Mbio. 2021 May 28;e0103121. Microb Pathog. 2020 Dec;149:104502. Pharmaceutics. 2021, 13(12), 2085. Research Square Preprint. 2022 Feb. [1]Seifert H, et al. In-vitro activity of the novel fluorocycline eravacycline against carbapenem non-susceptible Acinetobacter baumannii. Int J Antimicrob Agents. 2017 Jul 10. [2]Zhao M, et al. In Vivo Pharmacodynamic Target Assessment of Eravacycline against Escherichia coli in a Murine Thigh Infection Model. Antimicrob Agents Chemother. 2017 Jun 27;61(7). [3]Xiao XY, et al. Fluorocyclines. 1. 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: a potent, broad spectrum antibacterial agent. J Med Chem. 2012 Jan 26;55(2):597-605. [4]Sutcliffe JA, et al. Antibacterial activity of eravacycline (TP-434), a novel fluorocycline, against hospital and community pathogens. Antimicrob Agents Chemother. 2013 Nov;57(11):5548-58. [5]Grossman TH, et al. Eravacycline (TP-434) is efficacious in animal models of infection. Antimicrob Agents Chemother. 2015 May;59(5):2567-71.
Smiles	O=C(NC(C(O)=C1C2=O)=CC(F)=C1C[C@@]3([H])C[C@@]4([H])[C@H](N(C)C)C(O)=C(C(N)=O)C([C@@]4(O)C(O)=C32)=O)CN5CCCC5
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	TP-434
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial; Beta-lactamase
Shipping Temperature	Room temperature
Molecular Weight	558.56
Product Description	Eravacycline is a potent and broad-spectrum antibacterial agent.
Manufacturer - Research Area	Infection
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection
Isoform	Tetracycline
Clinical information	Launched

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Menge: 5 mg

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