Sancycline

ArtNr	HY-17466-10mg
Hersteller	MedChem Express
CAS-Nr.	808-26-4
Menge	10 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Kategorie	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Specific against	other
Purity	98.01
Citations	[1]Li G, et al. A brief overview of classical natural product drug synthesis and bioactivity[J]. Organic Chemistry Frontiers, 2022, 9(2): 517-571.\|[2]Gordon MK, et al. Doxycycline hydrogels as a potential therapy for ocular vesicant injury[J]. J Ocul Pharmacol Ther. 2010 Oct;26(5):407-19. \|[3]Nikita Shanmugam, et al. Abraham solvation parameter model: determination of experiment-based solute descriptor values for 3,5-dimethoxybenzoic acid based on measured solubility data[J]. Physics and Chemistry of Liquids. 2024. 62: 2: 89-100.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Bonomycin,6-Demethyl-6-deoxytetracycline
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	414.41
Product Description	Sancycline (6-Demethyl-6-deoxytetracycline) acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin[1][2][3].
Manufacturer - Research Area	Metabolic Disease; Inflammation/Immunology
Solubility	DMSO: 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection
Isoform	Tetracycline
Clinical information	No Development Reported

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HY-17466-10mg-safety-datasheet.pdf