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Demeclocycline (hydrochloride)

Demeclocycline (hydrochloride)

ArtNr	HY-17560-500mg
Hersteller	MedChem Express
CAS-Nr.	64-73-3
Menge	500 mg
Quantity options	100 mg 10 mM/1 mL 500 mg
Kategorie	Oncology Food Safety Antibiotics Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Specific against	other
Purity	95.15
Citations	[1]I Chopra, et al. Tetracyclines, molecular and clinical aspects. J Antimicrob Chemother. 1992 Mar;29(3):245-77. \|[2]D Schnappinger, et al. Tetracyclines: antibiotic action, uptake, and resistance mechanisms. Arch Microbiol. 1996 Jun;165(6):359-69. \|[3]Marleen L A Kortenoeven, et al. Demeclocycline attenuates hyponatremia by reducing aquaporin-2 expression in the renal inner medulla. Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1705-18. \|[4]Susobhan Sarkar, et al. Demeclocycline Reduces the Growth of Human Brain Tumor-Initiating Cells: Direct Activity and Through Monocytes. Front Immunol. 2020 Feb 21;11:272. Chemosphere. 2019 Jun:225:378-387. Mol Syst Biol. 2022 Sep;18(9):e11081. Patent. US20230014181. J Hazard Mater Adv. 2025 Nov 12;20:100939. J Photoch Photobio A. 2020 May.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])[C@H](O)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4Cl)N.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	64-73-3
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Category	Reference compound / Active compounds; API; Natural Products
Manufacturer - Targets	Antibiotic; Bacterial
Manufacturer - HS Code	H302+H312+H332, H315, H319, H335, H341
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, sealed storage, away from moisture)
Molecular Weight	501.31
Product Description	Demeclocycline hydrochloride is an orally active tetracycline antibiotic that inhibits the binding of aminoacyl tRNA by binding to the 30S ribosomal subunit, thereby affecting protein synthesis. Demeclocycline hydrochloride exhibits antibacterial activity against a broad spectrum of bacterial infections[1][2].
Manufacturer - Research Area	Cancer; Infection; Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic)\|H2O : 33.33 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	Launched
Isoform	Tetracycline
UNSPSC Code	12352005
Precautionary	H302+H312+H332, H315, H319, H335, H341

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