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Quercetin Europäischer Partner

ArtNr HY-18085-5g
Hersteller MedChem Express
CAS-Nr. 117-39-5
Menge 5 g
Quantity options 10mM/1mL 1 g 500 mg 5 g
Kategorie
Typ Inhibitors
Clon N/A
Specific against other
Purity 99.80
Formula C15H10O7
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[1]Leyre Navarro-Núñez, et al. Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases. Fitoterapia. 2010 Mar;81(2):75-80.
[2]Yu XB, et al. Inhibitory effects of protein kinase C inhibitors on tumor necrosis factor induced bovine pulmonary artery endothelial cell injuries. Yao Xue Xue Bao. 1996;31(3):176-81.
[3]Yang F, et al. Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth. PLoS One. 2015 May 26;10(5):e0128277.
[4]Tao Liu, et al. Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. Life Sci. 2020 Jul 20;118116.
Smiles OC1=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1=O
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 117-39-5
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Natural Products
Manufacturer - Applications
Cancer-Kinase/protease
Manufacturer - Targets
Apoptosis; Autophagy; Mitophagy; PI3K; Reactive Oxygen Species
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
302.24
Product Description
Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively[1].
Manufacturer - Research Area
Cancer
Solubility
DMSO : 100 mg/mL (ultrasonic)|Ethanol : 16.67 mg/mL (ultrasonic)
Manufacturer - Pathway
Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Isoform
PI3Kβ; PI3Kγ; PI3Kδ
Clinical information
Launched

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5 g
Lieferbar: In stock
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