Tigecycline

ArtNr	HY-B0117-500mg
Hersteller	MedChem Express
CAS-Nr.	220620-09-7
Menge	500 mg
Quantity options	100 mg 10 mM/1 mL 10 mg 200 mg 500 mg 50 mg 5 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Specific against	other
Purity	99.95
Citations	[1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9(5):e95281.\|[2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52(2):269-271. Adv Ther (Weinh). 2024 Jan 12.\|Animal Diseases. 02 November 2021.\|Ann Clin Microbiol Antimicrob. 2024 Aug 20;23(1):73.\|Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19.\|Antimicrob Agents Chemother. 2023 Jan 23;e0145922.\|Antimicrob Agents Chemother. 2024 Jan 30:e0112023.\|Antimicrob Agents Chemother. 2024 Oct 29:e0094524.\|Biomed Pharmacother. 2023 Nov 8:115856.\|Clin Exp Pharmacol Physiol. 2023 Apr 22.\|Cureus. 2024 Dec 1;16(12):e74917.\|EBioMedicine. 2022 Apr;78:103943.\|Infect Drug Resist. 2020 Jul 28;13:2617-2629.\|Infect Drug Resist. 2021 Jun 30;14:2499-2507.\|Infect Drug Resist. 2023 Apr 17.\|Int J Antimicrob Agents. 2018 Aug;52(2):269-271.\|J Antibiot (Tokyo). 2022 Jun 27.\|Microb Pathog. 2020 Dec;149:104502.\|Microbiol Spectr. 2022 Dec 8;e0323822.\|Microbiol Spectr. 2023 May 4;e0071823.\|Microorganisms. 2024 Mar 13, 12(3), 575.\|Nat Commun. 2022 Mar 2;13(1):1116.\|Nat Commun. 2024 Jun 28;15(1):5481.\|SLAS Discov. 2020 Sep;25(8):895-905.\|Vet Microbiol. 2024 May, 292, 110046.\|World J Microbiol Biotechnol. 2024 Jun 6;40(8):233.\|Ann Lab Med. 2021 May 1;41(3):293-301.\|Emerg Microbes Infect. 2024 Dec;13(1):2321981.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GAR-936
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-immunoregulation
Manufacturer - Targets	Antibiotic; Autophagy; Bacterial
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	585.65
Product Description	Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
Manufacturer - Research Area	Infection; Cancer
Solubility	DMSO: 25 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O: 8.33 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection; Autophagy
Clinical information	Launched

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HY-B0117-500mg-safety-datasheet.pdf