Pefloxacin (mesylate dihydrate)

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 500mg
ArtNr HY-B0147B-500mg
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
Pefloxacinium mesylate dihydrate
CAS No.
149676-40-4
Purity
>98%
MW
4654936
Formula
C18H28FN3O8S
Solubility
10 mM in DMSO
Biological Description
Pefloxacin mesylate dehydrate is a an antibacterial agent and prevents bacterial DNA replication by inhibiting DNA gyrase (topoisomerse)
Target: DNA gyrase
Pefloxacin is a synthetic chemotherapeutic agent used to treat severe and life-threatening bacterial infections. Pefloxacin is commonly referred to as afluoroquinolone (or quinolone) drug and is a member of the fluoroquinolone class of antibacterials. It is an analog of norfloxacin. It is a synthetic fluoroquinolone, belonging to the 3rd generation of quinolones. Pefloxacin is extensively prescribed in France. Pefloxacin has not been approved for use in the United States.
The bactericidal action of pefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited.
Menge: 500mg
Lieferbar: In stock
Listenpreis: 155,00 €
Preis: 155,00 €
lieferbar

Angebot anfordern

Fragen zum Produkt?

Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de

Schließen